Compile Data Set for Download or QSAR

Found 1144 hits of kd data for polymerid = 8469   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520138 (CHEMBL4463776) Show SMILES Cc1cc(CN2CCc3c(cc(Cn4ccn(C)c4=N)cc3-c3ccc(F)cc3C)C2=O)ccc1F Show InChI InChI=1S/C29H28F2N4O/c1-18-13-22(30)5-6-23(18)25-14-21(17-35-11-10-33(3)29(35)32)15-26-24(25)8-9-34(28(26)36)16-20-4-7-27(31)19(2)12-20/h4-7,10-15,32H,8-9,16-17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	<0.0200	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520131 (CHEMBL4588661) Show SMILES COc1cc(CN2CCc3c(cc(Cn4ccn(C)c4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1 Show InChI InChI=1S/C30H31FN4O3/c1-19-11-22(31)5-6-25(19)27-14-21(18-35-10-9-33(2)30(35)32)15-28-26(27)7-8-34(29(28)36)17-20-12-23(37-3)16-24(13-20)38-4/h5-6,9-16,32H,7-8,17-18H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	<0.0200	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520141 (CHEMBL4462065) Show SMILES COc1cc(CN2CCc3c(cc(Cn4ccoc4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1 Show InChI InChI=1S/C29H28FN3O4/c1-18-10-21(30)4-5-24(18)26-13-20(17-33-8-9-37-29(33)31)14-27-25(26)6-7-32(28(27)34)16-19-11-22(35-2)15-23(12-19)36-3/h4-5,8-15,31H,6-7,16-17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	<0.0200	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520135 (CHEMBL4463486) Show SMILES COc1cc(CN2CCc3c(cc(Cn4cnn(C)c4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1 Show InChI InChI=1S/C29H30FN5O3/c1-18-9-21(30)5-6-24(18)26-12-20(16-35-17-32-33(2)29(35)31)13-27-25(26)7-8-34(28(27)36)15-19-10-22(37-3)14-23(11-19)38-4/h5-6,9-14,17,31H,7-8,15-16H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.0230	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520120 (CHEMBL4476662) Show SMILES Cc1cc(CN2CCc3c(cc(Cn4ccn(C)c4=N)cc3-c3ccc(F)cc3C)C2=O)ccc1Cl Show InChI InChI=1S/C29H28ClFN4O/c1-18-13-22(31)5-6-23(18)25-14-21(17-35-11-10-33(3)29(35)32)15-26-24(25)8-9-34(28(26)36)16-20-4-7-27(30)19(2)12-20/h4-7,10-15,32H,8-9,16-17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.0270	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520126 (CHEMBL4557848) Show SMILES Cc1cc(F)ccc1-c1cc(Cn2ccn(C)c2=N)cc(c1)C(=O)NCc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C26H23Cl2FN4O/c1-16-9-21(29)4-5-22(16)19-10-18(15-33-8-7-32(2)26(33)30)11-20(13-19)25(34)31-14-17-3-6-23(27)24(28)12-17/h3-13,30H,14-15H2,1-2H3,(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520139 (CHEMBL4534270) Show SMILES COc1cc(CN2CCc3c(cc(CNC(=N)C4CC4)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1 Show InChI InChI=1S/C30H32FN3O3/c1-18-10-22(31)6-7-25(18)27-13-19(16-33-29(32)21-4-5-21)14-28-26(27)8-9-34(30(28)35)17-20-11-23(36-2)15-24(12-20)37-3/h6-7,10-15,21H,4-5,8-9,16-17H2,1-3H3,(H2,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520127 (CHEMBL4585441 | US10844044, Example 87) Show SMILES Cc1cc(CNC(=O)c2cc(Cn3ccn(C)c3=N)cc(c2)-c2ccc(F)cc2C)ccc1F Show InChI InChI=1S/C27H26F2N4O/c1-17-11-23(28)5-6-24(17)21-12-20(16-33-9-8-32(3)27(33)30)13-22(14-21)26(34)31-15-19-4-7-25(29)18(2)10-19/h4-14,30H,15-16H2,1-3H3,(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.0320	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520133 (CHEMBL4530969) Show SMILES COc1cc(CN2CCc3c(cc(CN4CCSC4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1 Show InChI InChI=1S/C29H30FN3O3S/c1-18-10-21(30)4-5-24(18)26-13-20(17-33-8-9-37-29(33)31)14-27-25(26)6-7-32(28(27)34)16-19-11-22(35-2)15-23(12-19)36-3/h4-5,10-15,31H,6-9,16-17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.0330	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520137 (CHEMBL4439051) Show SMILES COc1cc(CNC(=O)c2cc(Cn3ccn(C)c3=N)cc(c2)-c2ccc(F)cc2C)ccc1F Show InChI InChI=1S/C27H26F2N4O2/c1-17-10-22(28)5-6-23(17)20-11-19(16-33-9-8-32(2)27(33)30)12-21(14-20)26(34)31-15-18-4-7-24(29)25(13-18)35-3/h4-14,30H,15-16H2,1-3H3,(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.0350	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520132 (CHEMBL4453355) Show SMILES COc1cc(CN2CCc3c(cc(Cn4ccn(C5CC5)c4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1 Show InChI InChI=1S/C32H33FN4O3/c1-20-12-23(33)4-7-27(20)29-15-22(19-36-10-11-37(32(36)34)24-5-6-24)16-30-28(29)8-9-35(31(30)38)18-21-13-25(39-2)17-26(14-21)40-3/h4,7,10-17,24,34H,5-6,8-9,18-19H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.0430	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520130 (CHEMBL4435250) Show SMILES COc1cc(CNC(=O)c2cc(Cn3ccn(C)c3=N)cc(c2)-c2ccc(F)cc2C)cc(OC)c1 Show InChI InChI=1S/C28H29FN4O3/c1-18-9-23(29)5-6-26(18)21-10-20(17-33-8-7-32(2)28(33)30)11-22(14-21)27(34)31-16-19-12-24(35-3)15-25(13-19)36-4/h5-15,30H,16-17H2,1-4H3,(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	0.0490	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair				3D Structure (crystal)
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520128 (CHEMBL4555492) Show SMILES Cc1cc(C)cc(CNC(=O)c2cc(Cn3ccn(C)c3=N)cc(c2)-c2ccc(F)cc2C)c1 Show InChI InChI=1S/C28H29FN4O/c1-18-9-19(2)11-21(10-18)16-31-27(34)24-14-22(17-33-8-7-32(4)28(33)30)13-23(15-24)26-6-5-25(29)12-20(26)3/h5-15,30H,16-17H2,1-4H3,(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.0550	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM552952 (N-[2-[(3S)-3,4- dimethylpiperazin-1-yl]- 4-fluoro-...) Show SMILES C[C@H]1CN(CCN1C)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cnc(nc1)N1CCOCC1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00037 BindingDB Entry DOI: 10.7270/Q2B85D61
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM552952 (N-[2-[(3S)-3,4- dimethylpiperazin-1-yl]- 4-fluoro-...) Show SMILES C[C@H]1CN(CCN1C)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cnc(nc1)N1CCOCC1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520129 (CHEMBL4593719) Show SMILES Cc1cc(F)ccc1-c1cc(Cn2ccn(C)c2=N)cc(c1)C(=O)NCc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C26H23Cl2FN4O/c1-16-7-23(29)3-4-24(16)19-8-18(15-33-6-5-32(2)26(33)30)9-20(12-19)25(34)31-14-17-10-21(27)13-22(28)11-17/h3-13,30H,14-15H2,1-2H3,(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.0610	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520134 (CHEMBL4556167) Show SMILES COc1cc(CN2CCc3c(cc(CN4CCCC4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1 Show InChI InChI=1S/C30H32FN3O3/c1-19-11-22(31)6-7-25(19)27-14-21(17-33-9-4-5-29(33)32)15-28-26(27)8-10-34(30(28)35)18-20-12-23(36-2)16-24(13-20)37-3/h6-7,11-16,32H,4-5,8-10,17-18H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.0630	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520140 (CHEMBL4474045) Show SMILES Cc1cc(CNC(=O)c2cc(Cn3ccn(C)c3=N)cc(c2)-c2ccc(F)cc2C)ccc1Cl Show InChI InChI=1S/C27H26ClFN4O/c1-17-11-23(29)5-6-24(17)21-12-20(16-33-9-8-32(3)27(33)30)13-22(14-21)26(34)31-15-19-4-7-25(28)18(2)10-19/h4-14,30H,15-16H2,1-3H3,(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.0900	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM553268 (N-[4-fluoro-5-(1-pyrimidin-2- yl-3,6-dihydro-2H-py...) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)C1=CCCN(C1)c1ncccn1 |r,t:33| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.0950	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM553331 (N-[5-[1-[5-[(dimethylamino) methyl]pyrimidin-2-yl]...) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)C1=CCN(CC1)c1ncc(CN(C)C)cn1 |r,t:33| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.0950	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM552984 (4-(difluoromethyl)-N-[4- fluoro-5-(2-morpholin-4- ...) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)F)-c1cnc(nc1)N1CCOCC1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM553342 (N-[4-fluoro-5-[1-[5-[(4- methylpiperazin-1- yl)met...) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)C1=CCCN(C1)c1ncc(CN2CCN(C)CC2)cn1 |r,t:33| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.108	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520125 (CHEMBL4578661) Show SMILES Cc1cc(F)ccc1-c1cc(Cn2ccn(C)c2=N)cc(c1)C(=O)NCc1cccc(Cl)c1 Show InChI InChI=1S/C26H24ClFN4O/c1-17-10-23(28)6-7-24(17)20-11-19(16-32-9-8-31(2)26(32)29)12-21(14-20)25(33)30-15-18-4-3-5-22(27)13-18/h3-14,29H,15-16H2,1-2H3,(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM553321 (4-(difluoromethyl)-N-[4- fluoro-5-[2-[rac-(2R,6S)-...) Show SMILES C[C@H]1CN(C[C@@H](C)O1)c1ncc(cn1)-c1cc(NC(=O)c2c[nH]c(=O)cc2C(F)F)c(cc1F)N1CCN(C)[C@@H](C)C1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.152	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520136 (CHEMBL4436638) Show SMILES COc1cccc(CNC(=O)c2cc(Cn3ccn(C)c3=N)cc(c2)-c2ccc(F)cc2C)c1 Show InChI InChI=1S/C27H27FN4O2/c1-18-11-23(28)7-8-25(18)21-12-20(17-32-10-9-31(2)27(32)29)13-22(15-21)26(33)30-16-19-5-4-6-24(14-19)34-3/h4-15,29H,16-17H2,1-3H3,(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM553053 (N-[5-[2-(dimethylamino) pyrimidin-5-yl]-4-fluoro-2...) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cnc(nc1)N(C)C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.168	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM553013 (N-[5-(6-acetamidopyridin- 3-yl)-4-fluoro-2-[rac-(3...) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1ccc(NC(C)=O)nc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.199	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM552987 (N-[2-[(3R)-3- (dimethylamino)pyrrolidin- 1-yl]-4-f...) Show SMILES CN(C)[C@@H]1CCN(C1)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cnc(nc1)N1CCOCC1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM553019 (N-[5-(3,4-dihydro-2H- 1,5-benzodioxepin-7-yl)- 4-f...) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1ccc2OCCCOc2c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.225	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM553335 (N-[4-fluoro-5-[1-(5- formylpyrimidin-2-yl)-3,6- di...) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)C1=CCCN(C1)c1ncc(C=O)cn1 |r,t:33| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.229	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM553117 (N-[4-fluoro-5-[1-[[4-(4- methylpiperazin-1- yl)phe...) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)C1=CCN(Cc2ccc(cc2)N2CCN(C)CC2)CC1 |r,t:33| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM553333 (N-[4-fluoro-5-[1-[5-[(4- methylpiperazin-1-yl)meth...) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)C1=CCN(CC1)c1ncc(CN2CCN(C)CC2)cn1 |r,t:33| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.231	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM553147 (N-[5-(6- acetamidopyridin-3-yl)-4- fluoro-2-[rac-(...) Show SMILES C[C@H]1CN(CCN1C)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1ccc(NC(C)=O)nc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.240	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM553288 (N-[4-fluoro-5-[2-[methyl- [rac-(3R)-oxolan-3- yl]a...) Show SMILES C[C@H]1CN(CCN1C)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cnc(nc1)N(C)[C@H]1CCOC1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.244	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM553291 (N-[4-fluoro-5-[1-(6- methoxypyrimidin-4-yl)- 3,6-d...) Show SMILES COc1cc(ncn1)N1CCC=C(C1)c1cc(NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)c(cc1F)N1C[C@H](C)N(C)[C@H](C)C1 |r,c:12| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.246	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM553516 (US11319299, Example 601 | propan-2-yl 5-[2-fluoro-...) Show SMILES CC(C)OC(=O)N1CCC=C(C1)c1cc(NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)c(cc1F)N1C[C@H](C)N(C)[C@H](C)C1 |r,c:9| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.271	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM553573 (4-fluoro-N-[4-fluoro-2- [rac-(3R)-3,4- dimethylpip...) Show SMILES C[C@H]1CN(CCO1)c1nccc(n1)-c1cc(NC(=O)c2ccc(F)cc2C(F)(F)F)c(cc1F)N1CCN(C)[C@@H](C)C1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.290	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM553648 (4-fluoro-N-[4-fluoro-2- [rac-(3R)-3,4- dimethylpip...) Show SMILES C[C@H]1COCCN1c1ncc(cn1)-c1cc(NC(=O)c2ccc(F)cc2C(F)(F)F)c(cc1F)N1CCN(C)[C@@H](C)C1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.290	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM553355 (4-fluoro-N-[4-fluoro-5-[2-[rac- (2R,6S)-2,6-dimeth...) Show SMILES C[C@H]1CN(C[C@@H](C)O1)c1ncc(cn1)-c1cc(NC(=O)c2ccc(F)cc2C(F)(F)F)c(cc1F)N1CCN(C)[C@@H](C)C1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.296	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM552953 (N-[4-fluoro-5-(2- morpholin-4-ylpyrimidin- 5-yl)-2...) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cnc(nc1)N1CCOCC1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM552989 (N-[5-[6- (cyclopropylmethoxy) pyridin-3-yl]-4-fluo...) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1ccc(OCC2CC2)nc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM553339 (N-[4-fluoro-5-[1-[5- (hydroxymethyl)pyrimidin-2-yl...) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)C1=CCCN(C1)c1ncc(CO)cn1 |r,t:33| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.302	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM553307 (4-fluoro-N-[4-fluoro-2- [rac-(3R,5S)-3,4,5- trimet...) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1ncc(cn1)-c1cc(NC(=O)c2ccc(F)cc2C(F)(F)F)c(cc1F)N1C[C@H](C)N(C)[C@H](C)C1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.310	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM553051 (N-[4-fluoro-5-[6-(oxan-4- yloxy)pyridin-3-yl]-2- [...) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1ccc(OC2CCOCC2)nc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.320	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM552953 (N-[4-fluoro-5-(2- morpholin-4-ylpyrimidin- 5-yl)-2...) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cnc(nc1)N1CCOCC1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.323	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM553034 (N-[4-fluoro-5-[6-(2- methoxyethoxy)pyridin- 3-yl]-...) Show SMILES COCCOc1ccc(cn1)-c1cc(NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)c(cc1F)N1C[C@H](C)N(C)[C@H](C)C1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.338	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM553109 (N-[4-fluoro-5-(2- piperazin-1-ylpyrimidin- 5-yl)-2...) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cnc(nc1)N1CCNCC1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.345	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM553530 (N-[5-[1-(5-cyano-1,3- thiazol-2-yl)-3,6-dihydro- 2...) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)C1=CCCN(C1)c1ncc(s1)C#N |r,t:33| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.375	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM553033 (N-[4-fluoro-5-(2- morpholin-4-ylpyridin-4- yl)-2-[...) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1ccnc(c1)N1CCOCC1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.391	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM553384 (N-[4-fluoro-5-[1-[5-[(4- methylpiperazin-1- yl)met...) Show SMILES C[C@H]1CN(C[C@@H](C)N1C)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)C1=CCN(C1)c1ncc(CN2CCN(C)CC2)cn1 |r,t:33| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.392	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...				Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6
					More data for this Ligand-Target Pair

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